This is the inside story of how AI cracked the protein folding code. In 2024, David Baker, Demis Hassabis and John Jumper won the Nobel Prize in Chemistry for these advances in computer-assisted protein design and structure prediction.
Proteins are biological nano-machines that perform a vast array of vital functions inside of every living organism. For more than half a century, scientists have looked to solve the central mystery of protein science: How does a one-dimensional string of molecules fold innately and near-instantaneously into a complex three-dimensional shape? In 2020, Google DeepMind entered a deep-learning algorithm called AlphaFold2 into the Olympics of protein folding — and to everyone’s shock and surprise, ended up so
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This is the inside story of how AI cracked the protein folding code. In 2024, David Baker, Demis Hassabis and John Jumper won the Nobel Prize in Chemistry for these advances in computer-assisted protein design and structure prediction.
Proteins are biological nano-machines that perform a vast array of vital functions inside of every living organism. For more than half a century, scientists have looked to solve the central mystery of protein science: How does a one-dimensional string of molecules fold innately and near-instantaneously into a complex three-dimensional shape? In 2020, Google DeepMind entered a deep-learning algorithm called AlphaFold2 into the Olympics of protein folding — and to everyone’s shock and surprise, ended up solving a key part of the puzzle. This breakthrough kick-started an AI revolution in biology research, clearing the path to revolutionary new techniques in protein design, which is the process of creating new and novel proteins that could solve some of the world's biggest problems.
Israel's unabated bombardments across the war-torn Gaza Strip have claimed the lives of 36 Palestinians, including 34 from northern Gaza, since dawn today, medical sources told Al Jazeera.
En el universo observable hay unas 200.000 millones de galaxias. Si cada galaxia tuviera el tamaño de un cereal de desayuno, el universo observable tendría 37 titanics de largo (unos 10 km). Si juntamos todas las galaxias del tamaño de un cereal y las vertemos en una pisicina de 25m x 12.5m x 1.8m, ¿crees que se llenaría la piscina?
"Este vídeo fue relativamente complicado debido a la cantidad de cereales o galaxias que tuve que renderizar a veces. Creo que en la toma en la que estoy "bajo el agua" rodeado de galaxias había como un millón a mi alrededor, ¡lo que hizo sudar un poco a mi ordenador! Tuve que hacer las galaxias un poco más pequeñas de lo que deberían para esa toma, porque de lo contrario era sólo un mar de luz blanca. Fue todo un reto conseguir la escala real de 200.000 millon
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En el universo observable hay unas 200.000 millones de galaxias. Si cada galaxia tuviera el tamaño de un cereal de desayuno, el universo observable tendría 37 titanics de largo (unos 10 km). Si juntamos todas las galaxias del tamaño de un cereal y las vertemos en una pisicina de 25m x 12.5m x 1.8m, ¿crees que se llenaría la piscina?
"Este vídeo fue relativamente complicado debido a la cantidad de cereales o galaxias que tuve que renderizar a veces. Creo que en la toma en la que estoy "bajo el agua" rodeado de galaxias había como un millón a mi alrededor, ¡lo que hizo sudar un poco a mi ordenador! Tuve que hacer las galaxias un poco más pequeñas de lo que deberían para esa toma, porque de lo contrario era sólo un mar de luz blanca. Fue todo un reto conseguir la escala real de 200.000 millones, pero en este caso me gustó mucho añadir la parte sobre cómo y por qué sabemos estas cosas. Hay tantas historias maravillosas en la ciencia sobre cómo sabemos las cosas."
This system of trade incentivizes more people to waste plastic and pollute, than use it wisely or cleanup like these people do. Ultimately we need to deal with this bad and global incentive because the balance is tilted in the wrong way.
I took a part in the World Clean Up Day 2024. An epic event which happens once a year. It unites millions of people all over the world with a mission to clean up nature. To find out more, participa...
Anyone know what's up with the Firefox fork Fennec? I got a warning the other day that there were security vulnerabilities in the app, and upon checking when the last version was compiled it was in August. The source cide link just takes me to Mozilla's repos.
Disabled the app and switched browsers for the moment, but wanted to know if anybody knows what's going on with it. If not, anybody know of any other Android Firefox forks that cut Mozilla things out?
Here's a chance to learn from one of the jazz piano greats of the Bay Area. He needs more signups to his channel before he can do a live event. This guy is worth watching even if you are not currently learning piano Subscribe here: youtube.com/@FredBlastinBarrie… #piano #music
After almost a year, I finally got my physical driving license card....and I am able to release a big blog post about it! tiotrom.com/2024/10/spanish-dr…
Many thanks to Videla and Tedla for becoming the new 200 for TROM supporters! tromsite.com/donate/ - as soon as we will manage our life and kick-start the TROMhome project, we will push TROM a lot more! The 200 for TROM support is essential for the survival of this project.
We are trying something unique by only accepting 5 Euros monthly donations to make it more sustainable for everyone.
If you want to know what people are supporting, see the donation page.
It's time for solutions that address the core problem of why most people choose the likes of GAFAM over secure, self-hostable options.
As he says here, don't expect someone to get a CS degree to simply be able to share photos and files with family and friends. I say, let's look to the pinnacle days of user interface design in the 60s and 70s or early like Braun.
Everything was knobs you turn, faders you slide or a button to push.
Claude: A design perspective on a personal decentralized home server | Nextcloud Conference 2024
Claude: A Design Perspective on a Personal Decentralized Home Server by Diede van Marle
In this lightning talk, Diede will present his master thesis project, "Claude," a personal home server designed with a strong focus on privacy and secure sharing. This talk will explore how design principles can be applied to create more private file storage solutions, drawing inspiration from self-hosting practices and peer-to-peer sharing. Diede will discuss the project's origins, the development process, and the key insights gained along the way.
The next step in Sam's A-Z program of ethics is to be a conscious consumer. Only consume when necessary and when you do, vote with your wallet for more ethical products and services
To make it easier on the wallet Sam has compiled a page of discounts ; however it is for the UK so not very relevant to me. If you are in the UK though go for it ethicalrevolution.co.uk/consum…
An exception is the cloud storage services Filen (German) and Sync (Canadian) which are available internationally. Coincidentally, I had recently done a search for privacy respecting and secure alternatives to Google and OneDrive, and independently settled upon these two very providers as the best deals! I did not even know Filen was non-fossil fuel powered although I'd been looking for that very thing. Filen has generous free storage and an amazing deal on a lifetime plan. Sync is very highly rated for collaborative features and file syncing if that's what you need. I got a lifetime pl
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The next step in Sam's A-Z program of ethics is to be a conscious consumer. Only consume when necessary and when you do, vote with your wallet for more ethical products and services
To make it easier on the wallet Sam has compiled a page of discounts ; however it is for the UK so not very relevant to me. If you are in the UK though go for it ethicalrevolution.co.uk/consum…
An exception is the cloud storage services Filen (German) and Sync (Canadian) which are available internationally. Coincidentally, I had recently done a search for privacy respecting and secure alternatives to Google and OneDrive, and independently settled upon these two very providers as the best deals! I did not even know Filen was non-fossil fuel powered although I'd been looking for that very thing. Filen has generous free storage and an amazing deal on a lifetime plan. Sync is very highly rated for collaborative features and file syncing if that's what you need. I got a lifetime plan with Filen and am using Sync's free allotment; I especially recommend Sync's interface for ease of use and would pick it's paid plan if I had higher needs, or was running a business.
The provincial government has interfered with free collective bargaining again—this time suspending the right to strike for education support workers at Edmonton Public Schools after they voted 97% in favour of job action.
The Alberta Minister of Jobs, Economy and Trade is, again, using an obscure piece of the Alberta Labour Code to restrict the right of education support workers to take job action by imposing a Disputes Inquiry Board (DIB) on CUPE Local 3550.
"If the United States were to undo its experiment with rampant inequality and return the distribution of income to the levels found in 1970, the housing crisis would disappear." - Blair Fix
we are looking for 1 person who can invest $30,000,000 in our holding
if you invest in us, we will give back the money you have given as $40,000,0000 after 1 year
you will make a profit of $10,000,000 in 1 year
we will sign a promissory note that we will give the money you gave in 1 year as $40,000,000
You will invest 30,000,000 dollars in our holding, and in one year, you will receive your money back as 40,000,000 dollars, meaning you will have made a profit of 10,000,000 dollars within a year.
Information about our holding and how you can invest in our holding and how we can give you back the money you invested are available on our website. For detailed information, you can review our website at the link below.
Sérgio lives on the edge of Brazil’s Atlantic Forest – a crucial but often overlooked ecosystem compared to the Amazon. Like much of the land in Brazil, Sérgio’s property had once been cleared of trees to make space for cattle grazing. Realizing that he can make a difference, Sérgio decided to restore the forest in his own backyard.
Fast forward 10 years and Sérgio has planted more than 11,000 trees. Thanks to the Ecosia community and our local partner, Instituto Espinaço, he hasn’t only restored his own land, but also brought life back to a small piece of Brazil’s forgotten forest.
Living on the edge of Brazil’s Atlantic Forest, Sérgio has made it his mission to restore it, starting in his own backyard. Ten years later, his hard work has paid off. Check out our latest video to see for yourself!
TFed 🚀🌍:blobcatpat:
in reply to Tio • • •some sentences in the tests: commas? Never heard about them…
In addition, a copypasta was found
"the ctrl-c ctrl-v masters"